What Is The Best Client-side Email Organization Software?

I currently use MS Outlook and NEO (Nelson Email Organizer) to sort my email. NEO is nice, but it doesn’t do everything that I want it to.
What is the best software to organize my email? I recieve several hundred emails a day, of which maybe 20 are important. I would like a system that:
– Allows me to access a number of POP accounts
– Allows me to respond “from” a variety of accounts
– Automatically sorts emails based on a variety of custom rules (email from certain people gets treated differently)
– Allows me to categorize emails into different categories and easily access those categories (like Gmail)
– Is a client-side application or plugin (Gmail is great, but I need to be able to work offline)
– Allows fast access to a by-contact view of my mail — I need to be able to very quickly sort by sender regardless of where the email is stored. (NEO is great at this).
I don’t care if I stick with the “folder” metaphor or not. Thunderbird?

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One Response to “What Is The Best Client-side Email Organization Software?”

1. mattster says:

   June 24, 2009 at 4:52 pm

   Actually thunderbird is great at this, especially in its sorting /categorizing features. You can sort by a lot of different fields, like sender name.
   It connects to many different pop accounts, and supports all other major types, except exchange, but it will do IMAP which exchange supports if you need that. Best part is that it is open source, has a STRONG community supporting and improving the product, and its free!